Clotrimazole Supplier

Xi'an Yihui Company is a professional manufacturer of Clotrimazole API. We can generate it with a 99.9% content. It can be utilized in food, medicine, health care items, or cosmetics and meet USP, BP, EP,CP standards. We can offer you products of the highest caliber at the most competitive rates. Your best option for a reputable pure Clotrimazole supplier is Xi'an Yihui Company!

 

Our advantage

Rich experice: we have 13 Years professional experience;

Customers all over the word: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

What is Clotrimazole?

99% Clotrimazole is a broad-spectrum antifungal agent that can also be used to treat protozoan infections. Its chemical name is 1-[β-(2, 4-dichlorophenyl) -cyclopropyl] -4-methyl-1H-imidazole,CAS NO. Is 23593-75-1. which is a white or white-like crystalline powder that is easily soluble in organic solvents such as water, ethanol and chloroform.

Clotrimazole API is an antifungal medication that is used to treat a variety of fungal infections. It belongs to a class of medications called azoles and works by inhibiting the growth of fungi. It is available in various forms such as creams, powders, and sprays for topical use, as well as in suppositories for vaginal use. It is also available in an oral form for the treatment of systemic fungal infections.

It is the active pharmaceutical ingredient found in medications that contain clotrimazole. It is the main component that provides the antifungal properties of the medication. The API is the purest form of the clotrimazole molecule, and it is used to manufacture various drug formulations. Its use ensures the consistency and potency of the medication produced.

It is produced through a complex chemical process that involves the isolation and purification of the clotrimazole molecule. The process typically involves synthesizing the molecule from precursor molecules or extracting it from natural sources. The purified is then further processed into various dosage forms such as tablets, creams, and suppositories.

Its use has revolutionized the treatment of fungal infections. This antifungal medication has proven to be effective against a broad spectrum of fungal pathogens, including dermatophytes, yeasts, and molds. It is also highly effective in treating chronic fungal infections and preventing their recurrence.

It has also been used in the development of combination therapies for the treatment of fungal infections. For example, It is combined with betamethasone, a corticosteroid, in the treatment of fungal infections that cause inflammation and itching. It can also be combined with other antifungal medications to enhance its effectiveness against resistant fungal infections.

In conclusion, It is an essential component in the pharmaceutical industry for the treatment of fungal infections. Its use has led to the development of various dosage forms and combination therapies that have improved the treatment outcomes for patients suffering from fungal infections.

 

Basic Information

Appearance	White to pale yellow, crystalline powder	Melting point	147-149°C	Structural formula:
CAS NO.	23593-75-1	Boiling point	501.14°C (rough estimate)
MF	C22H17ClN2	Density	1.1095 (rough estimate)
MW	344.84	refractive index	1.5940 (estimate)
EINECS	245-764-8	solubility Soluble	in chloroform, DMSO, DMF and alcohols
Assay	min99%	storage temp.	2-8°C

 

Quality standard：

TEST ITEM	SPECIFICATION
1.Characteristics	White to pale yellow, crystalline powder. Melts at about 142,with decomposition. Practically insoluble in water; freely soluble in methanol, in acetone, in chloroform, and in alcohol.
2.Identification   Â	Infrared Absorption <197>
	The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.（HPLC）
3.Related compound A	≤0.5%
4.Imidazole	≤0.5%
5.Loss on drying	≤0.5%
6.Residue On Ignition	≤0.1%
7.Heavy Metals	≤0.001%
8.Assay	98%-102%(C22H17ClN2) Calculated on dried basis
  9.Residual Solvent	Benzene≤2ppm
	Acetonitrile≤5000ppm
10.Microorganism	TPC<1000cfu/g
	Y and M <100cfu/g
	E-coli – absent
	Staphylococcus Aureus-Absent
	Pseudomonas Aeruginosa-Absent
	Albicans Saccharomyces-Absent

 

Functions

99% Clotrimazole is a widely used antifungal agent that has numerous applications in the pharmaceutical industry. As an API (Active Pharmaceutical Ingredient), it has several important functions that make it an essential component in various medications.

1. Antifungal Activity: it is primarily used for its antifungal activity. It inhibits the growth of fungi by preventing the synthesis of ergosterol, an essential component of fungal cell membranes. With its broad spectrum of activity against several fungal species, clotrimazole is used in the treatment of various fungal infections, including thrush, ringworm, and athlete's foot.

2. Anti-Inflammatory Activity: it has also been found to have anti-inflammatory properties. In addition to inhibiting fungal growth, it can also help alleviate the symptoms of inflammation by reducing the release of inflammatory cytokines.

3. Antibacterial Activity: In addition to its antifungal activity, it also has some antibacterial properties. It has been shown to inhibit the growth of certain Gram-positive and Gram-negative bacteria.

4. Topical Application: it is commonly used in topical formulations such as creams, ointments, and powders. When applied topically, it can penetrate the skin and reach the site of infection to effectively treat fungal and bacterial infections.

5. Low Toxicity: it has low toxicity, making it a safe and effective treatment option even for vulnerable populations such as children and pregnant women.

6. Combination Therapy: it is often combined with other antifungal agents to increase its spectrum of activity and improve treatment outcomes. For example, it is often used in combination with betamethasone in the treatment of certain skin conditions like eczema.

In conclusion, it is a versatile antifungal agent that has several important functions in the pharmaceutical industry. Its antifungal, anti-inflammatory, and antibacterial properties, combined with its low toxicity and easy topical application, make it an attractive option for the treatment of various fungal and bacterial infections.

 

Application

Clotrimazole API is a synthetic antifungal compound used in various pharmaceutical and personal care products. It belongs to the imidazole family of compounds and works by inhibiting the growth of fungi. it is commonly found in over-the-counter creams, lotions, and sprays used for the treatment of skin infections like athlete's foot, ringworm, and jock itch.

In addition to its antifungal properties, it is also used as an ingredient in certain topical creams and ointments used for the treatment of eczema, psoriasis, and other skin conditions. It is often combined with other active ingredients to provide a synergistic effect and increase the overall efficacy of the product.

it has also been used in veterinary medicine as a treatment for certain fungal infections in animals. It is typically administered topically or in the form of an oral medication.

Overall, it is a versatile compound with a wide range of applications in the pharmaceutical and personal care industries. Its antifungal properties make it a valuable ingredient in many products used for the treatment of fungal infections, while its use in treating other skin conditions further expands its usefulness.

 

Only for commercial or research use , not supply for any individual!

Packing：

1kg/foil bag; 5kg/carton; 25kg/fiber drum; or packing as your request. Customization: Customized logo Customized packaging Graphic customization   Lead time: Within 3 workdays after receiving payment.

Shipping：

Item	Quantity	ETA time	Shipping Method
By Courier	≤50kg	7-15days	By express door to door Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient
By Air	50kg~200kg	3-5days	By air Fast and cheap
By Sea	Large quantity	20-35days	By sea Cheapest way

 

 

Xi'an Yihui company is a professional enterprise engaged in the research and development, production and sales of pharmaceutical raw materials, as well as one of the professional manufacturers of clotrimazole api. The company is committed to the research and development of high quality biologic drugs and innovative drugs, with a wide range of market channels and customer groups. Xi 'an Yihui Company has more than 10 years of production experience in the production of 99% clotrimazole, with advanced production equipment and technology. At the same time, we strictly control the procurement of raw materials and the production process to ensure the quality and stability of products. Clotrimazole provided by Xi 'an Yihui Company are mainly used in the pharmaceutical industry of antifungal drugs, widely used in the treatment of dandruff, oral leukopleckles, skin fungal infections and other diseases. Companies adhering to the advanced scientific and technological concepts, pay attention to originality and innovation ability, improve their own competitive advantages in the pharmaceutical industry, in order to meet the needs of the market.

 

if you need clotrimazole, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com

Tel: 0086-29-89695240

WeChat or WhatsApp: 0086-17792415937

http://www.yihuipharm.com/